Laser Microbeam and Medical Program
From BTRR
Overview
The program is designed to develop optical instrumentation and biophysical models for understanding mechanisms of light-tissue interaction.
Current Research
Mechanisms of coherent image formation; models for understanding the origin and degradation of coherent light interactions in biological tissues; and combined two-photon excited fluorescence and second harmonic generation imaging in vivo. Applications include monitoring/imaging hemodynamics before, during, and after interventional procedures and imaging cell-extracellular matrix interactions.
Tissue absorption and scattering measurements in complex, heterogeneous, and biological systems; relations between tissue optical properties and physiology/cellular structure; and tissue phantoms, preclinical animal models, and human subjects. Applications include tumor diagnostics in breast, brain, and cervix and the structural origins of tissue optical properties.
